UFH (unfractionated heparin)
Category: Pharmaceutical and Medical
Exhibitor: BIONOVAX CORP
Booth No: M928
Unfractionated heparin (UFH) is a glycosaminoglycans (GAGs) with a molecular weight between 3,000 and 40000 Da (average molecular weight between 15,000 and 19,000 Da), which is mainly extracted from the porcine intestinal mucosa. An active pharmaceutical ingredient (API) composed of highly sulfated mucopolysaccharides, appears a white or almost white powder which is hygroscopic and readily soluble in water to be acidic. Usually heparin drugs are formulated as "injectables" and used as "subcutaneous injections" or "intravenous injections" because of their ability to bind unto antithrombin III and to inhibit the affinity between multiple coagulation factors (Factor Xa, IIa, XIa, XIIa etc.). Substantially, the cascade accelerates the inactivation of thrombin, which results in very significant anticoagulant function in vivo or in vitro. It has been widely used in the treatment and auxiliary use while medical or surgical operations (especially cardiovascular or dialysis patients). For example, it is used as an anticoagulant drug in artificial heart-lung, peritoneal dialysis, or hemodialysis, as in vitro anticoagulants during transfusion for blood prevention and blood bank preservation. As the world’s population ages, so do cardiovascular and cerebrovascular diseases, heparin is indeed the most important and commonly used antithrombotic and anticoagulant.
Our UFH is manufactured from API pharmaceutical factory complied with PIC/S GMP standards. Therefore, our UFH possesses high quality, stable activity, and meet the internationally recognized USP and EP standards to provide downstream drug-product pharmaceutical manufacturer for developing various doses of injection-type products. In addition, our UFH can also be used as a standard for biochemical tests or assays and as an anticoagulant spread in vacutainer for blood sampling.
Products you may be interested in